To put go fuck yourself on a whole other level.

where in the lab, a subject is transformed from one species to another

A short band of large anal beads, 2-4 beads. at the very ends of each bulb, a portal device. Just insert one bead inside and anally fuck someone, either a constant inward motion, constant expulsion, or pistoning back and forth, the beads moving in between both portal ends inside and outside the ass. For even extra intimate fun, get two devices between two persons, and switch portal ends. Every-time beads goes inside one person, the same beads go out the other, and vice versa.

Mutate a subject's tongue into a cock. Can be great when combining with kissing and sucking, as well as gathering more samples

Having Strap-ons available and for each genital type (Like canine, equine, feline) for females to use.

Have a subjects balls get bigger or tighter or have the vagina swollen and puffy from prolonged edging and denial

I'm thinking a few tools, each used to "inflate" the subject in a way... 

1) Rubber Synthesizer: A chemical to inject the subject with in order to inflate

2) Pump: Just a basic bike pump, slow to inflate

3) Motor Pump: A faster and automatic pump. Set an inflate rate

4) Cum Stimulizer: A chemical you inject yourself with, allowing you to produce enough cum to inflate a subject affected by the Rubber Synthesiser

5) Water Bottle: A basic think to inflate the subject with water...

 That's all I can think of at the moment... Trying to keep the ideas realistic twords the game, requiring science stuff and such. Oh, and perhaps the ability or option to inflate specific body parts, such as the breasts, or cock, or feet, etc etc, or the entire body together, rather then only a select few parts or whole body only.

A Room in which subjects can be tied suspended in air or trapped in wall for anyone to use as they please.